Karl Aegidi was Physician to Princess Fredericka of Prussia. He proposed to Hahnemann that he:
“administer a mixture of two highly potentized remedies, each corresponding to different parts of the disease.
In the potentized state the medicines thus mixed would be incapable of chemical reaction but would each act separately in its own sphere.”
Hahnemann was persuaded that this would lead to polypharmacy and he excluded it from the Organon.
Lutze seized upon the idea, and in his unauthorized 6th edition of the Organon suggested that Hahnemann favored polypharmacy.